NPPB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12298-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12298-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12298-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12298-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NPPB
Background:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:150
Immunogen:
Synthetic peptide of human NPPB
Purification method:
Affinity purification
Target Synonym:
ANFB;BNP;BNP(1-32);BNP(5-29);BNP-32;Brain type natriuretic peptide;Gamma brain natriuretic peptide;Gamma-brain natriuretic peptide;Natriuretic peptide precursor B;nppb;NT proBNP
UNIProt ID:
P16860