NPHS2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16657-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16657-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16657-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16657-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NPHS2
Background:
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NPHS2
Purification method:
Affinity purification
Target Synonym:
Nephrosis 2;idiopathic;steroid resistant (podocin);nephrosis 2;idiopathic;steroid resistant;NPHS2;NPHS2 gene;PDCN;PODO;Podocin;SRN1
UNIProt ID:
Q9NP85
References
- https://www.tandfonline.com/doi/abs/10.1080/1354750X.2022.2157489