NOD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13109-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13109-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13109-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13109-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NOD2
Background:
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NOD2
Purification method:
Affinity purification
Target Synonym:
ACUG;Arthrocutaneouveal granulomatosis;BLAU;CARD15;Caspase recruitment domain family;member 15;Caspase recruitment domain protein 15;Caspase recruitment domain-containing protein 15;CD;CLR16.3;IBD1;Inflammatory bowel disease protein 1;LRR containing protein;NLR family;CARD domain containing 2;NLRC2;NOD like receptor C2;NOD2;NOD2 protein;NOD2;NOD2B;nucleotide binding oligomerization domain 2;Nucleotide binding oligomerization domain containing 2;Nucleotide binding oligomerization domain;leucine rich repeat and CARD domain containing 2;Nucleotide-binding oligomerization domain-containing protein 2;PSORAS1
UNIProt ID:
Q9HC29