NOD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16300-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16300-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16300-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16300-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NOD1
Background:
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NOD1
Purification method:
Affinity purification
Target Synonym:
CARD 4;CARD4;Caspase recruitment domain 4;Caspase recruitment domain containing protein 4;Caspase recruitment domain family member 4;Caspase recruitment domain protein 4;Caspase recruitment domain-containing protein 4;CLR 7.1;CLR7.1;NLR family CARD domain containing 1;NLRC 1;NLRC1;NOD 1;Nod1;NOD1 protein;NOD1;Nucleotide binding oligomerization domain containing 1;Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1;Nucleotide-binding oligomerization domain-containing protein 1;Protein Nod1
UNIProt ID:
Q9Y239