NLRP7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16254-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16254-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16254-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16254-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NLRP7
Background:
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human NLRP7
Purification method:
Affinity purification
Target Synonym:
CLR19.4;FLJ94610;HYDM;MGC126470;MGC126471;NACHT;leucine rich repeat and PYD containing 7;NACHT;LRR and PYD containing protein 7;NACHT;LRR and PYD domains containing protein 7;NACHT;LRR and PYD domains-containing protein 7;NALP7;NALP7;NLR family;pyrin domain containing 7;NLRP7;NOD12;Nucleotide-binding oligomerization domain protein 12;Nucleotide-binding oligomerization domain;leucine rich repeat and pyrin domain containing 7;PAN7;PYPAF3;PYRIN-containing APAF1-like protein 3
UNIProt ID:
Q8WX94