NLRP4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16628-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16628-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16628-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16628-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NLRP4
Background:
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NLRP4
Purification method:
Affinity purification
Target Synonym:
Cancer/testis antigen 58;CLR19.5;CT58;FLJ32126;NACHT;leucine rich repeat and PYD containing 4;NACHT;LRR and PYD containing protein 4;NACHT;LRR and PYD domains-containing protein 4;NALP4;NLR family;pyrin domain containing 4;NLRP4;Nucleotide binding oligomerization domain;leucine rich repeat and pyrin domain containing 4;PAAD and NACHT containing protein 2;PAAD and NACHT-containing protein 2;PAN2;PYPAF4;PYRIN and NACHT-containing protein 2;PYRIN containing APAF1 like protein 4;PYRIN-containing APAF1-like protein 4;Ribonuclease inhibitor 2;RNH2
UNIProt ID:
Q96MN2