NLRP10 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16648-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16648-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16648-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16648-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NLRP10
Background:
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NLRP10
Purification method:
Affinity purification
Target Synonym:
CLR11.1;NACHT;leucine rich repeat and PYD containing 10;NACHT;LRR and PYD domains containing protein 10;NACHT;LRR and PYD domains-containing protein 10;NAL10;NALP10;NLR family;pyrin domain containing 10;Nlrp10;NOD8;Nucleotide-binding oligomerization domain protein 8;Nucleotide-binding oligomerization domain;leucine rich repeat and pyrin domain containing 10;PAN5;PYNOD
UNIProt ID:
Q86W26