NEDD4L Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15252-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15252-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15252-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15252-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NEDD4L
Background:
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human NEDD4L
Purification method:
Affinity purification
Target Synonym:
E3 ubiquitin protein ligase NEDD4 like protein;E3 ubiquitin-protein ligase NEDD4-like;KIAA0439;NED4L;NEDD4 2;NEDD4 2c;Nedd4-2;NEDD4-2a;NEDD4.2;NEDD4b;NEDD4L;NEDD4La;NEDD4Lb;NEDD4Lc;NEDD4Ld;NEDD4Le;NEDD4Lf;NEDD4Lg;NEDD4Lh;NEDL3;Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase;Neural precursor cell expressed;developmentally down regulated 4 like;RSP5;Ubiquitin protein ligase Rsp5
UNIProt ID:
Q96PU5