NSMCE3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16215-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16215-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16215-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16215-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NDNL2
Background:
The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
34kDa
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NDNL2
Purification method:
Affinity purification
Target Synonym:
HCA4;hepatocellular carcinoma-associated protein 4;hepatocellular carcinoma-associated protein HCA4;MAGE-G1 antigen;MAGEG1;MAGEL3;melanoma antigen;family G;1;melanoma-associated antigen G1;necdin-like 2;necdin-like gene 2;necdin-like protein 2;NSE3;NSMCE3
UNIProt ID:
Q96MG7