NCR2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13122-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13122-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13122-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13122-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NCR2
Background:
Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NCR2
Purification method:
Affinity purification
Target Synonym:
Activating NK receptor NKp44;CD336;CD336 antigen;dJ149M18.1;LY95;Lymphocyte antigen 95 (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog;Lymphocyte antigen 95;mouse;homolog of;Natural cytotoxicity triggering receptor 2;Natural killer cell p44 related protein;Natural killer cell p44-related protein;NCR2;NCTR2;NK cell activating receptor (NKp44);NK cell activating receptor;NK cell-activating receptor;NK p44;NK-p44;NKp44
UNIProt ID:
O95944