NBN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15798-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15798-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15798-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15798-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
NBN
Background:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human NBN
Purification method:
Affinity purification
Target Synonym:
AT V1;AT V2;ATV;Cell cycle regulatory protein p95;FLJ10155;MGC87362;Nbn;NBN;NBS 1;NBS;NBS1;Nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome;Nijmegen breakage syndrome protein 1;p95;p95 protein of the MRE11/RAD50 complex
UNIProt ID:
O60934