MYSM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12793-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12793-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12793-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12793-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MYSM1
Background:
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MYSM1
Purification method:
Affinity purification
Target Synonym:
2A-DUB;2ADUB;Histone H2A deubiquitinase;Histone H2A deubiquitinase MYSM1;KIAA1915;Myb like SWIRM and MPN domains 1;Myb like;SWIRM and MPN domain containing protein;Myb like;SWIRM and MPN domains 1;Myb-like;Myb-like;SWIRM and MPN domains 1;MYSM 1;mysm1;MYSM1 Myb-like;SWIRM and MPN domains 1;MYSM1;RP4-592A1.1;SWIRM and MPN domain-containing protein 1
UNIProt ID:
Q5VVJ2