MUTYH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10477-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10477-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10477-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10477-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MUTYH
Background:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
60kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human MUTYH
Purification method:
Affinity purification
Target Synonym:
A/G specific adenine DNA glycosylase;A/G-specific adenine DNA glycosylase;Adenine DNA glycosylase;CYP2C;hMYH;MGC4416;MutY (E. coli) homolog;MutY homolog (E. coli);MutY homolog;MutY;E. coli;homolog of;Mutyh;MUTYH;MYH;rMYH
UNIProt ID:
Q9UIF7