MTNR1A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12579-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12579-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12579-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12579-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MTNR1A
Background:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
39kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human MTNR1A
Purification method:
Affinity purification
Target Synonym:
Mel 1A R;MEL-1A-R;Mel1a melatonin receptor;Mel1a receptor;Melatonin receptor 1A;Melatonin receptor type 1A;MelR;MR;MT 1;MT1;MTNR 1A;MTNR1A;MTR1A
UNIProt ID:
P48039
References
- https://journals.sagepub.com/doi/abs/10.1177/09603271221149010