MT-ND6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16622-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16622-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16622-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16622-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MT-ND6
Background:
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MT-ND6
Purification method:
Affinity purification
Target Synonym:
Mitochondrially encoded NADH dehydrogenase 6;MT ND6;mtND6;NADH dehydrogenase subunit 6 (complex I);NADH ubiquinone oxidoreductase chain 6;NADH Ubiquinone Oxidoreductase subunit ND6;NADH6;ND6
UNIProt ID:
P03923