MT-ND1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13427-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13427-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13427-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13427-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MT-ND1
Background:
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
36kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MT-ND1
Purification method:
Affinity purification
Target Synonym:
Complex I;subunit ND1;Mitochondrially encoded NADH dehydrogenase 1;MT-ND1;MTND1;NAD1;NADH dehydrogenase subunit 1 (complex I);NADH dehydrogenase subunit 1;NADH-ubiquinone oxidoreductase chain 1;NADH-ubiquinone oxidoreductase;subunit ND1;NADH1;ND1;NU1M
UNIProt ID:
P03886