MSH4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10467-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10467-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10467-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10467-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MSH4
Background:
This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human MSH4
Purification method:
Affinity purification
Target Synonym:
hMSH4;MSH 4;MSH4;MSH4;MutS homolog 4 (E. Coli);MutS homolog 4;MutS protein homolog 4
UNIProt ID:
O15457