MPG Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10980-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10980-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10980-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10980-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MPG
Background:
Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
32kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human MPG
Purification method:
Affinity purification
Target Synonym:
3 alkyladenine DNA glycosylase;3-alkyladenine DNA glycosylase;3-methyladenine DNA glycosidase;3MG;AAG;ADPG;Alkyladenine DNA glycosylase;anpg;APNG;CRA36.1;DNA 3 methyladenine glycosylase;DNA-3-methyladenine glycosylase;MDG;Mid1;Mpg;N methylpurine DNA glycosirase;N methylpurine DNA glycosylase;N-methylpurine-DNA glycosylase;PIG11;PIG16;Proliferation inducing protein 11;Proliferation inducing protein 16
UNIProt ID:
P29372