MMP8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15777-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15777-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15777-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15777-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MMP8
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
53kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human MMP8
Purification method:
Affinity purification
Target Synonym:
CLG 1;CLG1;Collagenase 1;Collagenase 1 neutrophil;HNC;Matrix metallopeptidase 8 (neutrophil collagenase);Matrix metalloprotease 8;Matrix metalloproteinase-8;MMP 8;MMP-8;Mmp8;MMP8;Neutrophil collagenase;PMNL CL;PMNL collagenase;PMNL-CL;PMNLCL
UNIProt ID:
P22894