MMP14 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-14218-20uL | 20uL | £125.00 |
Quantity:
E-AB-14218-60uL | 60uL | £172.00 |
Quantity:
E-AB-14218-120uL | 120uL | £237.00 |
Quantity:
E-AB-14218-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
MMP14
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human MMP14
Purification method:
Affinity purification
Target Synonym:
Matrix metallopeptidase 14 (membrane inserted);Matrix metalloproteinase 14;Matrix metalloproteinase-14;Membrane type 1 matrix metalloproteinase;Membrane type 1 metalloprotease;Membrane type matrix metalloproteinase 1;Membrane-type matrix metalloproteinase 1;Membrane-type-1 matrix metalloproteinase;MMP 14;MMP X1;MMP-14;MMP-X1;Mmp14;MMP14;MMPX1;MT MMP 1;MT-MMP 1;MT1 MMP;MT1-MMP;MT1MMP;MTMMP 1;MTMMP1
UNIProt ID:
P50281