MMP12 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14217-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14217-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14217-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14217-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MMP12
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human MMP12
Purification method:
Affinity purification
Target Synonym:
EC 3.4.24.65;HME;Macrophage elastase;Macrophage metalloelastase;Macrophage metaloelastase;Matrix metallopeptidase 12 (macrophage elastase);Matrix metalloprotease 12;Matrix metalloproteinase-12;ME;MGC138506;MME;MMP 12;MMP-12;Mmp12;MMP12
UNIProt ID:
P39900