MMP11 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15781-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15781-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15781-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15781-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MMP11
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
55kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MMP11
Purification method:
Affinity purification
Target Synonym:
Matrix Metalloproteinase 11;Matrix metalloproteinase-11;MMP-11;Mmp11;MMP11;SL 3;SL-3;SL3;ST3;STMY3;Stromelysin 3;Stromelysin III;Stromelysin-3
UNIProt ID:
P24347