MECP2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15195-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15195-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15195-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15195-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MECP2
Background:
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
52kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human MECP2
Purification method:
Affinity purification
Target Synonym:
AUTSX 3;AUTSX3;DKFZp686A24160;Mbd 5;Mbd5;MECP 2;MeCP 2 protein;MeCP-2 protein;Mecp2;MECP2;Methyl CpG binding protein 2 (Rett syndrome);Methyl CpG binding protein 2;Methyl-CpG-binding protein 2;MRX 16;MRX 79;MRX16;MRX79;MRXS 13;MRXS13;MRXSL;PPMX;RS;RTS;RTT;WBP 10;WBP10
UNIProt ID:
P51608