MCM6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10451-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10451-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10451-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10451-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MCM6
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
93kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human MCM6
Purification method:
Affinity purification
Target Synonym:
DNA replication licensing factor MCM6;MCG40308;Mcm6;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog;S. pombe);MCM6 minichromosome maintenance deficient 6;MCM6;Minichromosome maintenance complex component 6;Minichromosome maintenance deficient (mis5 S. pombe) 6;Minichromosome maintenance deficient 6 homolog;Minichromosome maintenance protein 6;Mis5;MIS5 homolog;p105MCM
UNIProt ID:
Q14566