MCM3AP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15058-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15058-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15058-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15058-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MCM3AP
Background:
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
218kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human MCM3AP
Purification method:
Affinity purification
Target Synonym:
80 kDa MCM3 associated protein;80 kDa MCM3-associated protein;FLJ44336;FLJ45306;Germinal center associated nuclear protein;KIAA0572;MAP80;MCM3 import protein;MCM3 minichromosome maintenance deficient 3 associated protein;MCM3A;MCM3A;Mcm3ap;Minichromosome maintenance complex component 3 associated protein;Minichromosome maintenance deficient 3 associated protein;Minichromosome maintenance protein 3 associated protein;Protein GANP;SAC3
UNIProt ID:
O60318