MCM3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14214-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14214-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14214-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14214-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MCM3
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
91kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human MCM3
Purification method:
Affinity purification
Target Synonym:
Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;DNA polymerase alpha holoenzyme associated protein P1;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor mcm3;HCC 5;HCC5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM 3;mcm3;MCM3 minichromosome maintenance deficient 3;MCM3;MGC1157;Minichromosome maintenance complex component 3;Minichromosome maintenance deficient 3;Minichromosome maintenance protein 3;P1 h;P1 MCM3;P1 Protein;P1-MCM3;P1.h;p102;P102 protein;Replication licensing factor beta subunit;RLF beta subunit;RLF subunit beta;RLFB
UNIProt ID:
P25205