ERK1/2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12397-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12397-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12397-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12397-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MAPK1/MAPK3
Background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
41/43kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MAPK1/MAPK3
Purification method:
Affinity purification
Target Synonym:
ERK1;ERK2;ERK1/2
UNIProt ID:
P28482,P27361
References
- https://onlinelibrary.wiley.com/doi/abs/10.1002/cjoc.202200392
- https://iovs.arvojournals.org/article.aspx?articleid=2670140