MAP3K12 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10631-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10631-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10631-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10631-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MAP3K12
Background:
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human MAP3K12
Purification method:
Affinity purification
Target Synonym:
Dlk;Dual leucine zipper bearing kinase;Dual leucine zipper kinase DLK;Leucine-zipper protein kinase;M3K12;Map3k12;MAPK-upstream kinase;MEKK12;Mitogen-activated protein kinase kinase kinase 12;Mixed lineage kinase;MUK;Protein kinase MUK;ZPK;ZPKP1
UNIProt ID:
Q12852