MANF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16174-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16174-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16174-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16174-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MANF
Background:
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MANF
Purification method:
Affinity purification
Target Synonym:
Arginine rich mutated in early stage tumors;Arginine rich protein;Arginine-rich protein;ARMET;ARMET protein;ARP;Manf;MANF;Mesencephalic astrocyte derived neurotrophic factor;Mesencephalic astrocyte-derived neurotrophic factor;MGC142148;MGC142150;Protein ARMET
UNIProt ID:
P55145