MAL Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16590-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16590-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16590-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16590-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MAL
Background:
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MAL
Purification method:
Affinity purification
Target Synonym:
mal;MAL protein gene;Mal T-cell differentiation protein;MAL;MALGENE;MPV17;Myelin and lymphocyte protein;T-cell differentiation protein MAL;T-lymphocyte maturation-associated protein;VIP17
UNIProt ID:
P21145