MAGEL2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13399-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13399-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13399-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13399-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
MAGEL2
Background:
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human MAGEL2
Purification method:
Affinity purification
Target Synonym:
Mage-l2;MAGE-like 2;MAGE-like protein 2;MAGEL2;melanoma antigen-like gene 2;NDNL1;Necdin like protein 1;necdin-like 1;nM15;ns7;Protein nM15;PWLS
UNIProt ID:
Q9UJ55