LZTFL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15183-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15183-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15183-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15183-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LZTFL1
Background:
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
35kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human LZTFL1
Purification method:
Affinity purification
Target Synonym:
5530402H04Rik;6130400H19Rik;AI414725;AW048545;BBS17;DKFZp686H2076;FLJ36386;Leucine zipper transcription factor like 1;Leucine zipper transcription factor like protein 1;Leucine zipper transcription factor-like protein 1;LZTFL 1;Lztfl1;Lztfl1 leucine zipper transcription factor-like 1;LZTL1;MGC106871;MGC108960;Putative uncharacterized protein DKFZp686H2076
UNIProt ID:
Q9NQ48