LRP5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15758-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15758-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15758-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15758-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LRP5
Background:
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human LRP5
Purification method:
Affinity purification
Target Synonym:
BMND1;EVR1;EVR4;HBM;Low density lipoprotein receptor related protein 5;Low density lipoprotein receptor related protein 7;Low-density lipoprotein receptor-related protein 5;LR3;LRP-5;Lrp5;LRP5;LRP7;OPPG;OPS;OPTA1;Osteoporosis pseudoglioma syndrome;VBCH2
UNIProt ID:
O75197