LOX Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15490-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15490-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15490-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15490-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LOX
Background:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
47kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human LOX
Purification method:
Affinity purification
Target Synonym:
lox;LYOX;LYOX;Lysyl oxidase;MGC105112;Protein lysine 6 oxidase;Protein-lysine 6-oxidase
UNIProt ID:
P28300