LIN28B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13008-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13008-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13008-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13008-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LIN28B
Background:
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
27kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human LIN28B
Purification method:
Affinity purification
Target Synonym:
CSDD 2;CSDD2;FLJ16517;Lin 28 homolog B (C. elegans);Lin 28.2;Lin-28B;LIN28B;LN28B;Protein lin-28 homolog B
UNIProt ID:
Q6ZN17