LIMK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13381-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13381-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13381-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13381-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LIMK1
Background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human LIMK1
Purification method:
Affinity purification
Target Synonym:
EC 2.7.1.37;LIM domain containing protein kinase;LIM domain kinase 1;LIM kinase;LIM motif containing protein kinase;LIMK 1;LIMK;LIMK-1;limk1;LIMK1
UNIProt ID:
P53667