LILRB1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10412-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10412-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10412-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10412-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LILRB1
Background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human LILRB1
Purification method:
Affinity purification
Target Synonym:
CD85;CD85 antigen;CD85 antigen like family member J;CD85 antigen-like family member J;CD85j;CD85j antigen;Ig like transcript 2;ILT 2;ILT-2;ILT2;immunoglobulin like transcript 2;Immunoglobulin-like transcript 2;leukocyte Ig like receptor 1;Leukocyte immunoglobulin like receptor 1;leukocyte immunoglobulin like receptor subfamily B member 1;Leukocyte immunoglobulin like receptor subfamily B member 1 precursor;leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform;leukocyte immunoglobulin like receptor;subfamily B;member 1;Leukocyte immunoglobulin-like receptor 1;Leukocyte immunoglobulin-like receptor subfamily B member 1;leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform;leukocyte immunoglobulin-like receptor;subfamily B (with TM and ITIM domains);member 1;LILRB1;LIR 1;LIR-1;LIR1;LIRB1;MIR 7;MIR-7;MIR7;Monocyte/macrophage immunoglobulin like receptor 7;Monocyte/macrophage immunoglobulin-like receptor 7;PIR B;PIRB
UNIProt ID:
Q8NHL6