DNA Ligase1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14958-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14958-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14958-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14958-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LIG1
Background:
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant protein of human LIG1
Purification method:
Affinity purification
Target Synonym:
DNA ligase 1;DNA ligase I;DNLI1;LIG 1;lig1;Ligase I DNA ATP dependent;MGC117397;MGC130025;Polydeoxyribonucleotide synthase [ATP] 1
UNIProt ID:
P18858