LEP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10070-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10070-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10070-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10070-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LEP
Background:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human LEP
Purification method:
Affinity purification
Target Synonym:
FLJ94114;LEP;LEP;LEPD;Leptin (murine obesity homolog);Leptin (obesity homolog;mouse);Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese protein;Obese;mouse;homolog of;Obesity;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285
UNIProt ID:
P41159