LATS2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15942-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15942-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15942-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15942-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
LATS2
Background:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human LATS2
Purification method:
Affinity purification
Target Synonym:
FLJ13161;Kinase phosphorylated during mitosis protein;KPM;Large tumor suppressor homolog 2;Large tumor suppressor homolog 2 Drosophila;Large tumor suppressor kinase 2;LATS large tumor suppressor Drosophila homolog 2;LATS large tumor suppressor homolog 2;Lats2;LATS2;Serine/threonine kinase kpm;Serine/threonine protein kinase kpm;Serine/threonine-protein kinase kpm;Serine/threonine-protein kinase LATS2;Warts like kinase;Warts-like kinase
UNIProt ID:
Q9NRM7