Laminin alpha5 Polyclonal Antibody

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Elabscience
Product Code: E-AB-31903
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-31903-20uL20uL£125.00
Quantity:
E-AB-31903-60uL60uL£172.00
Quantity:
E-AB-31903-120uL120uL£237.00
Quantity:
E-AB-31903-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of RAW264.7, HepG2, A549 cells with Laminin alpha5 Polyclonal Antibody
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Western Blot analysis of RAW264.7, HepG2, A549 cells with Laminin alpha5 Polyclonal Antibody

Documents

Further Information

Abbreviation:
Laminin α-5
Background:
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
400kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Immunogen:
Synthesized peptide derived from the Internal region of human Laminin α-5
ObservedMW:
400kDa
Purification method:
Affinity purification
Target Synonym:
LAMA5;KIAA0533;KIAA1907;Laminin subunit alpha-5;Laminin-10 subunit alpha;Laminin-11 subunit alpha;Laminin-15 subunit alpha
UNIProt ID:
O15230

References

  • https://www.sciencedirect.com/science/article/pii/S2352396419303275
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535067/
  • https://www.sciencedirect.com/science/article/pii/S0014483518305578