LMNA Polyclonal Antibody

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Elabscience
Product Code: E-AB-31899
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-31899-20uL20uL£125.00
Quantity:
E-AB-31899-60uL60uL£172.00
Quantity:
E-AB-31899-120uL120uL£237.00
Quantity:
E-AB-31899-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Immunohistochemistry of paraffin-embedded Human uterus tissue using LMNA Polyclonal Antibody at dilution of 1:200.
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Immunohistochemistry of paraffin-embedded Human uterus tissue using LMNA Polyclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
Lamin A/C
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
74kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.
ObservedMW:
74kDa,65kDa
Purification method:
Affinity purification
Target Synonym:
70 kDa lamin;Cardiomyopathy dilated 1A (autosomal dominant);CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;Lamin A;Lamin A/C;Lamin A/C like 1;Lamin;Lamin C;Lamin-A/C;LDP1;LFP;LGMD1B;Limb girdle muscular dystrophy 1B (autosomal dominant);LMN 1;LMN A;LMN C;LMN1;LMNA;LMNA;LMNC;LMNL1;Prelamin A/C;PRO1;Renal carcinoma antigen NY REN 32;Renal carcinoma antigen NY-REN-32;Renal carcinoma antigen NYREN32
UNIProt ID:
P02545

References

  • https://www.sciencedirect.com/science/article/pii/S0898656821000164