L1CAM Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16230-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16230-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16230-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16230-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
L1CAM
Background:
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human L1CAM
Purification method:
Affinity purification
Target Synonym:
Antigen identified by monoclonal R1;CAML1;CD171;CD171 antigen;HSAS;HSAS1;Hyd;L1;L1 cell adhesion molecule;L1-NCAM;L1cam;L1CAM;MASA;MIC5;N CAML1;N-CAM-L1;NCAM-L1;NCAML1;Nerve-growth factor-inducible large external glycoprotein;Neural cell adhesion molecule L1;NILE;OTTHUMP00000025992;S10;SPG1
UNIProt ID:
P32004