KPNB1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13334-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13334-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13334-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13334-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
KPNB1
Background:
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human KPNB1
Purification method:
Affinity purification
Target Synonym:
IMB 1;IMB1;IMB1;Impnb;Importin 90;Importin beta 1;Importin beta 1 subunit;Importin subunit beta-1;Importin-90;IPOB;Karyopherin beta 1;Karyopherin beta 1 subunit;Karyopherin subunit beta-1;KPNB 1;Kpnb1;MGC2155;MGC2156;MGC2157;NTF 97;NTF97;Nuclear factor P97;Pore targeting complex 97 kDa subunit;PTAC97
UNIProt ID:
Q14974