KLK7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14181-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14181-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14181-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14181-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
KLK7
Background:
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
28kDa
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human KLK7
Purification method:
Affinity purification
Target Synonym:
Chymotryptic stratum corneum;hK 7;hK7;hSCCE;Kallikrein 7 (chymotryptic stratum corneum);Kallikrein related peptidase 7;Kallikrein-7;Kallikrein7;KLK 7;Klk7;KLK7;Protease serine 6;PRSS 6;PRSS6;SCCE;Serine protease 6;Signal protein;Stratum corneum chymotryptic enzyme
UNIProt ID:
P49862