KLC1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10932-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10932-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10932-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10932-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
KLC1
Background:
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
65kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human KLC1
Purification method:
Affinity purification
Target Synonym:
Kinesin 2 60/70kDa;Kinesin light chain 1;Kinesin2;KLC 1;KLC;Klc1;KLC1;KNS 2;KNS 2A;KNS2;KNS2A;Medulloblastoma antigen MU MB 2.50;MGC15245
UNIProt ID:
Q07866