KIF3A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10420-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10420-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10420-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10420-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
KIF3A
Background:
Kinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
80kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant protein of human KIF3A
Purification method:
Affinity purification
Target Synonym:
KIF 3;KIF 3A;KIF3;Kif3a;KIF3A;Kifl;Kinesin family member 3A;Kinesin family protein 3;Kinesin family protein 3A;Kinesin like protein KIF 3A;Kinesin like protein KIF3A;Kinesin-like protein KIF3A;Kns3;Microtubule plus end directed kinesin motor 3A;Microtubule plus end-directed kinesin motor 3A
UNIProt ID:
Q9Y496