KIF7 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22026-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22026-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22026-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22026-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:3I4
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Kif 7
Background:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300, IF 1:50-200
Immunogen:
Synthetic Peptide
Purification method:
Protein A purification
Target Synonym:
EQYK340;kif7;KIF7;kinesin family member 7;kinesin like protein KIF7;Kinesin-like protein kif7;UNQ340
UNIProt ID:
Q2M1P5