KDM5B Polyclonal Antibody

Elabscience
Product Code: E-AB-13360
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-13360-20uL20uL£125.00
Quantity:
E-AB-13360-60uL60uL£172.00
Quantity:
E-AB-13360-120uL120uL£237.00
Quantity:
E-AB-13360-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C

Documents

Further Information

Abbreviation:
KDM5B
Background:
PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human KDM5B
Purification method:
Affinity purification
Target Synonym:
Cancer/testis antigen 31;CT31;Histone demethylase JARID1B;JARID1B;Jumonji AT rich interactive domain 1B;Jumonji/ARID domain-containing protein 1B;Kdm5b;KDM5B;Lysine (K) specific demethylase 5B;Lysine demethylase 5B;Lysine specific demethylase 5B;Lysine-specific demethylase 5B;PLU-1;PLU1;PPP1R98;Protein phosphatase 1 regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2 like;RBP2-H1;Retinoblastoma-binding protein 2 homolog 1;Retinoblastoma-binding protein 2 homolog 1A
UNIProt ID:
Q9UGL1