KCNA1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15740-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15740-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15740-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15740-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
KCNA1
Background:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
56kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:15-1:50
Immunogen:
Synthetic peptide of human KCNA1
Purification method:
Affinity purification
Target Synonym:
AEMK;EA1;Episodic ataxia with myokymia;HBK1;HUK1;Kca1 1;Kcna1;KCNA1;Kcpvd;KV1.1;MBK1;mceph;MGC124402;MGC126782;MGC138385;MK1;MK1;mouse;homolog of KV1.1;Potassium channel protein 1;Potassium voltage gated channel shaker related subfamily member 1;Potassium voltage gated channel subfamily A member 1;Potassium voltage gated channel;shaker related subfamily;member 1 (episodic ataxia with myokymia);Potassium voltage-gated channel subfamily A member 1;RBK1;RCK1;Shak;Shaker related subfamily member 1;Voltage gated potassium channel subunit Kv1.1;Voltage-gated K(+) channel HuKI;Voltage-gated potassium channel HBK1;Voltage-gated potassium channel subunit Kv1.1
UNIProt ID:
Q09470